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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSC3
All Species:
10.61
Human Site:
T755
Identified Species:
25.93
UniProt:
Q14574
Number Species:
9
Phosphosite Substitution
Charge Score:
0.56
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14574
NP_001932.2
896
99969
T755
A
N
G
F
M
T
Q
T
T
N
N
S
S
Q
G
Chimpanzee
Pan troglodytes
XP_512076
896
99727
T755
A
N
G
F
M
T
Q
T
A
N
N
S
S
Q
G
Rhesus Macaque
Macaca mulatta
XP_001102096
954
105079
T813
A
N
G
F
T
T
Q
T
V
G
A
S
A
Q
G
Dog
Lupus familis
XP_866930
902
100740
T761
T
D
G
F
T
T
H
T
V
G
S
S
A
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P55850
895
100636
P754
C
S
A
W
I
H
H
P
H
C
Q
Q
L
Q
P
Rat
Rattus norvegicus
Q9Z1Y3
906
99668
E776
N
I
L
K
Y
D
E
E
G
G
G
E
E
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515354
1013
112098
D872
G
P
G
E
E
V
M
D
A
N
I
R
L
P
N
Chicken
Gallus gallus
P10288
912
100446
E782
N
I
L
K
Y
D
E
E
G
G
G
E
E
D
Q
Frog
Xenopus laevis
P79883
922
101155
E791
D
N
I
L
K
Y
D
E
E
G
G
G
E
E
D
Zebra Danio
Brachydanio rerio
Q90275
893
98972
E763
N
I
L
K
Y
D
E
E
G
G
G
E
E
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
63.6
64.5
N.A.
76.9
32.4
N.A.
48.2
32.4
32.5
32.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
76.4
79.1
N.A.
86
50
N.A.
62.9
50.2
50.3
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
66.6
46.6
N.A.
6.6
0
N.A.
13.3
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
73.3
66.6
N.A.
26.6
6.6
N.A.
13.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
10
0
0
0
0
0
20
0
10
0
20
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
30
10
10
0
0
0
0
0
30
10
% D
% Glu:
0
0
0
10
10
0
30
40
10
0
0
30
40
10
0
% E
% Phe:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
50
0
0
0
0
0
30
60
40
10
0
0
40
% G
% His:
0
0
0
0
0
10
20
0
10
0
0
0
0
0
0
% H
% Ile:
0
30
10
0
10
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
30
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
30
10
0
0
0
0
0
0
0
0
20
0
0
% L
% Met:
0
0
0
0
20
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
30
40
0
0
0
0
0
0
0
30
20
0
0
0
10
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
30
0
0
0
10
10
0
50
30
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
10
40
20
0
0
% S
% Thr:
10
0
0
0
20
40
0
40
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
30
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _